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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
10.91
Human Site:
T212
Identified Species:
17.14
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
T212
G
A
S
P
P
T
G
T
N
R
H
G
M
K
A
Chimpanzee
Pan troglodytes
XP_510301
627
67581
K191
R
L
L
P
G
R
V
K
G
S
P
K
K
R
L
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
T212
G
A
S
P
P
T
T
T
G
R
R
G
M
K
A
Dog
Lupus familis
XP_544614
968
105825
T499
G
T
S
P
P
T
A
T
S
R
R
G
T
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
T213
G
T
S
P
P
M
A
T
G
R
R
G
V
K
V
Rat
Rattus norvegicus
Q62829
544
60692
T108
L
L
Q
T
S
N
I
T
K
L
E
Q
K
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
E203
A
A
P
P
G
R
A
E
K
A
T
Q
R
S
S
Chicken
Gallus gallus
XP_426393
667
74767
M212
L
P
G
D
G
D
K
M
G
K
R
S
S
E
E
Frog
Xenopus laevis
NP_001082100
650
73749
D207
G
N
D
R
G
H
S
D
P
V
E
R
V
V
K
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
P212
P
V
P
E
P
P
R
P
L
Y
L
A
G
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
N203
N
S
Q
H
A
H
A
N
G
A
T
G
P
L
A
Honey Bee
Apis mellifera
XP_001122147
624
70155
P188
P
N
L
Q
N
L
N
P
N
M
Q
S
S
P
N
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
Y136
S
G
Q
K
W
L
Q
Y
D
M
M
F
I
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
E363
G
E
Y
T
G
L
P
E
E
W
E
K
L
L
T
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
E361
Q
F
T
G
L
P
K
E
W
Q
R
L
I
S
E
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
80
66.6
N.A.
53.3
13.3
N.A.
13.3
0
6.6
6.6
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
13.3
80
73.3
N.A.
60
13.3
N.A.
20
13.3
13.3
6.6
N.A.
20
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
0
0
7
0
27
0
0
14
0
7
0
0
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
7
0
7
7
0
0
0
0
14
7
% D
% Glu:
0
7
0
7
0
0
0
20
7
0
20
0
0
7
14
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
40
7
7
7
34
0
7
0
34
0
0
34
7
0
0
% G
% His:
0
0
0
7
0
14
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
0
0
14
0
7
% I
% Lys:
0
0
0
7
0
0
14
7
14
7
0
14
14
34
7
% K
% Leu:
14
14
14
0
7
20
0
0
7
7
7
7
7
14
7
% L
% Met:
0
0
0
0
0
7
0
7
0
14
7
0
14
0
0
% M
% Asn:
7
14
0
0
7
7
7
7
14
0
0
0
0
0
14
% N
% Pro:
14
7
14
40
34
14
7
14
7
0
7
0
7
7
0
% P
% Gln:
7
0
20
7
0
0
7
0
0
7
7
14
0
0
0
% Q
% Arg:
7
0
0
7
0
14
7
0
0
27
34
7
7
7
0
% R
% Ser:
7
7
27
0
7
0
7
0
7
7
0
14
14
14
7
% S
% Thr:
0
14
7
14
0
20
7
34
0
0
14
0
7
0
7
% T
% Val:
0
7
0
0
0
0
7
0
0
7
0
0
14
7
7
% V
% Trp:
0
0
0
0
7
0
0
0
7
7
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
7
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _